One object of the invention is to provide new compounds and pharmaceutically acceptable salts thereof useful for the prevention or treatment of conditions such as cancerous angiogenesis, chronic rheumatoid arthritis, endothelial hypertrophy, atherosclerosis, hemorrhagic cerebral stroke, acute myocardial infarction, chronic heart failure, aneurism, cancer metastasis, adult respiratory distress syndrome, asthma, idiopathic pulmonary fibrosis, chronic paranasal sinusitis, bronchitis, or chronic obstructive pulmonary disease. The invention provides the compounds of formula (I) and pharmaceutically acceptable salts thereof.本發明係以提供對於癌性血管新生、慢性關節風濕、血管內膜肥厚、血管粥狀硬化症、出血性型腦中風、急性心肌梗塞、慢性心臟衰竭、動脈瘤、癌轉移、成人呼吸窘迫症候群、氣喘、特發性肺纖維化症、慢性副鼻腔炎、支氣管炎、或慢性閉塞性肺疾病等疾病之預防或治療上有用之新穎化合物或其醫藥上可被許可之鹽為目的者。本發明提供式(I)所示化合物或其醫藥上可被許可之鹽。
