PROBLEM TO BE SOLVED: To provide a method for prevention and/or treatment of cardiovascular disease, chronic rheumatic arthritis, skin cancer, diabetes, premenstrual syndrome and its increased transdermal delivery thereof.SOLUTION: Provided is an administration of a therapeutically effective amount of krill oil and/or oil from marine organisms. Also, provided is a composition for prevention and/treatment of the diseases.COPYRIGHT: (C)2013,JPO&INPIT【課題】心臓血管疾患、慢性関節リウマチ、皮膚ガン、糖尿病、月経前症候群および経皮送達増強の予防および/または治療法の提供。【解決手段】療治効果的な量のオキアミ油および/または海洋生物油を患者に投与すること。また、これら疾患の予防および/または治療のための組成物。【選択図】なし