Mark Edward Bunnage,Andrew Simon Cook,Jingrong Jean Cui,Kevin Nell Dack,Judith Gail Deal,Danlin Gu,Mingying He,Patrick Stephen Johnson,Ted William Johnson,Phuong Thi Quy Le,Cynthia Louise Palmer,Hong
申请号:
US13695770
公开号:
US08916593B2
申请日:
2011.05.04
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention relates to compounds of Formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases in which ALK protein is involved or in which inhibition of ALK activity may induce benefit, especially for the treatment of cancer mediated by a mutated EML4-ALK fusion protein.