BUNNAGE, MARK EDWARD,COOK, ANDREW SIMON,CUI, JINGRONG JEAN,DACK, KEVIN NEIL,DEAL, JUDITH GAIL,GU, DANLIN,HE, MINGYING,JOHNSON, PATRICK STEPHEN,JOHNSON, TED WILLIAM,LE, PHUONG THI QUY,PALMER, CYNTHIA L
申请号:
CA2796967
公开号:
CA2796967C
申请日:
2011.05.04
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The invention relates to compounds of Formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases in which ALK protein is involved or in which inhibition of ALK activity may induce benefit, especially for the treatment of cancer mediated by a mutated EML4-ALK fusion protein.