The present invention provides an injection device including a syringe (12) having a distal end for receiving a needle, and a plunger inserted into the proximal end. A guard (14) is slidable on the syringe, has a proximal end, a distal end, and is biased from a first position wherein the needle is exposed toward a second position wherein the guard covers the needle. The syringe includes a body having a central cylindrical opening for receiving medicine and the plunger, and further includes a pair of longitudinally extending members (18) on opposite sides of the body. The guard has an interior configuration for mating with the longitudinal members and sliding thereon.