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TRICYCLIC COMPOUNDS, COMPOSITIONS CONTAINING THE SPECIFIED COMPOUNDS AND THEIR APPLICATIONS
专利权人:
Йиссум Ресерч Девелопмент Компани оф де Хебрю Юниверсити оф Джерусалем Лтд. (IL)
发明人:
БЕН-САССОН Шмуэль (IL),ДАГАН Арие (IL),ПЕРЛЕС Шарон (IL)
申请号:
RU2014119711/04
公开号:
RU2014119711A
申请日:
2012.11.15
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. The compound of general formula (I): 1 each of R-R is independently selected from the group consisting of H, OH, SH, halogen, nitro, amino, nitrilo, nitroso, acetyl, acetamido, acylamido, alkylamino, linear or branched C-alkyl , linear or branched C-Calkenyl, linear or branched C-Calkynyl, amine, linear or branched C-Calkoxy, linear or branched C-C carboxyl, linear or branched C-C ester, linear or branched C-Cthoxy, linear or branched C-Cioxy, -Sulfinyl and linear or branched C-Cthionyl; R and R are independently selected from the absence of a radical, linear or branched C-Calkyl, linear or branched C-Calkenyl, linear or branched C-Calkynyl, piperazinyl, pyridinyl, piperidinyl, morpholinyl and thiomorpholinyl, at least one of which; R and R are substituted by at least one quaternary amino group or phosphonium; X is selected from CH, N and P; Y is selected from the missing radical, CH, N, P, CH, NH, O, S, CH-CH, CH = CH, C = O and NO = O.2. A compound according to claim 1, wherein X is N and Y is an absent radical. A compound according to claim 1 or 2, wherein R4 represents a linear or branched C-C1-6 alkyl. A compound according to claim 3, wherein said linear or branched C 1 -C 6 alkyl is substituted with at least one quaternary amino group. A compound according to claim 4, wherein said at least one quaternary amino group has the general formula (V): wherein each of R ′, R ″ and R ″ ″ is independently selected from the group consisting of linear or branched C-C 1-6 alkyl, linear or branched C-alkenyl and linear or branched C-alkynyl. 6. The compound of claim 5, wherein each of R ′, R ″ and1. Соединение общей формулы (I):1гдекаждый из R-Rнезависимо выбран из группы, состоящей из H, OH, SH, галогена, нитро, амино, нитрило, нитрозо, ацетила, ацетамидо, ациламидо, алкиламино, линейного или разветвленного C-Cалкила, линейного или разветвленного C-Cалкенила, линейного или разветвленного C-Cалкинила, амина, линейного или разветвленного C-Cалкокси, линейного или разветвл
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