PROBLEM TO BE SOLVED: To provide an endoplasmic reticulum stress inhibitor and a nerve cell death inhibitor with high efficacy and reduced side effects. SOLUTION: General formula: Z-A-COOH [In the formula, Z is hydrogen or an aromatic hydrocarbon group or a heterocyclic group which may have a substituent, and A has a substituent. Which is a saturated or unsaturated hydrocarbon group which may be present] and an endoplasmic reticulum stress inhibitor containing a compound, and a nerve cell death inhibitor containing the above compound. [Selection diagram] None【課題】有効性が高く、副作用が軽減された小胞体ストレス抑制剤および神経細胞死抑制剤を提供する。【解決手段】一般式： Ｚ－Ａ－ＣＯＯＨ［式中、Ｚは水素であるか、または置換基を有してもよい芳香族炭化水素基もしくは複素環基であり、Ａは置換基を有してもよい飽和または不飽和炭化水素基である］で表される化合物を含む小胞体ストレス抑制剤、および上記化合物を含む神経細胞死抑制剤。【選択図】なし
