Vaccine comprising a peptide bound to a pharmaceutically acceptable carrier, said peptide having the amino acid sequence €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ (X 1 ) m (X 2 ) n (X 3 ) o X 4 X 5 H P X 6 €ƒ€ƒ€ƒ€ƒ€ƒ(Formula I), for treating and/or preventing a physical disorder associated with the renin-activated angiotensin system, wherein X 1 is D, X 2 is A, P, M, or R, X 3 is G, A, H, or V, X 4 is Y, X 5 is A, D, or I, X 6 is F, wherein mis independently 0 or 1 and n and o are 1, and wherein the peptide is not DRVYIHPF or RVYIHPF.
