Vaccine comprising a peptide bound to a pharmaceutically acceptable carrier, said peptide having the amino acid sequence (X1)m (X2)n (X3)o X4 X5 H P X6 (Formula I),for treating and/or preventing a physical disorder associated with the renin-activated angiotensin system, whereinX1 is D,X2 is A, P, M, or R,X3 is G, A, H, or V,X4 is Y,X5 is A, D, or I,X6 is F,wherein mis independently 0 or 1 and n and o are 1, and wherein the peptide is not DRVYIHPF or RVYIHPF.
