A dispensing device and the method of making same for dispensing medicaments to a patient that includes a housing, a first assembly connected to the first end of the housing that includes a body portion, and a penetrating sub-assembly. The first assembly also includes a rate control chip of novel construction that is connected to the penetrating sub-assembly and functions to control the rate of flow of medicinal fluid to the patient. Disposed within the housing is a second assembly that includes a shuttle, a collapsible container carried by the shuttle and a plurality of variable force springs that function to thrust the collapsible container into penetrating engagement with the penetrating member of the penetrating assembly and then to collapse the collapsible container to deliver the medicinal fluid to the patient. Connected to the second end of the housing is a novel third assembly that includes an operating member that is threadably connected to the shuttle. The operating member functions to controllably move the shuttle forwardly of the housing. The apparatus also includes a novel locking mechanism that releasably locks the operating member against rotation relative to the shuttle.薬物を患者に投与する投与装置は、ハウジングと、ハウジングの第1の端部に接続され、本体部分、貫入サブアセンブリを含む第1のアセンブリとを含む。第1のアセンブリは、貫入サブアセンブリに接続され、患者へ向かう薬液の流速を制御する流速制御チップを含む。ハウジング内には第2のアセンブリがあり、シャトル、シャトルに担持される折り畳み式容器、貫入部材と貫入係合しかつ折り畳み式容器を折り畳んで薬液を供給するように折り畳み式容器を押し進める複数の可変力ばねを含む。ハウジングの第2の端部には、シャトルにねじ接続されている動作部材を含む第3のアセンブリが接続されている。動作部材は、シャトルをハウジングの前方に制御式に動かす。また、シャトルに対して回転しないように動作部材を解除式にロックするロッキング機構も含む。【選択図】図2