ЛЭБОДИНЬЕР Ричард Фредерик (US),О'НЕЙЛ Майкл Генри (US),ОНЕЙЛ Майкл Генри (US)
申请号：
RU2014109676/04
公开号：
RU2014109676A
申请日:
2012.09.12
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
1. The crystalline form of meglumine 6-carboxy-2- (3,5-dichlorophenyl) benzoxazole, where the crystalline form has a powder x-ray containing peaks at diffraction angles (2θ) 10.7 ± 0.2, 11.8 ± 0 , 2 and 13.3 ± 0.2.2. The crystalline form according to claim 1, wherein said crystalline form has a powder X-ray diffraction pattern containing peaks at diffraction angles (2θ) of 10.7 ± 0.2, 11.8 ± 0.2, 13.3 ± 0.2 and 14.8 ± 0.2.3. The crystalline form according to claim 1, wherein said crystalline form has a powder X-ray diffraction pattern containing peaks at diffraction angles (2θ) of 10.7 ± 0.2, 11.8 ± 0.2, 13.3 ± 0.2, 14.8 ± 0.2 and 21.7 ± 0.2.4. The crystalline form according to claim 1, wherein said crystalline form has a Raman spectrum containing a shift of Raman peaks (cm) at 1625 ± 2, 1596 ± 2 and 1548 ± 2.5. The crystalline form according to claim 1, wherein said crystalline form has a Raman spectrum containing a shift of Raman peaks (cm) at 1625 ± 2, 1616 ± 2, 1596 ± 2 and 1548 ± 2.6. The crystalline form according to claim 1, wherein said crystalline form has an infrared spectrum containing a shift of infrared peaks (cm) at 1581 ± 2, 1273 ± 2, 1010 ± 2, 906 ± 2 and 873 ± 2.7. The crystalline form according to claim 1, wherein said crystalline form has a solid state NMR spectrum including C chemical shifts (ppm) at 112.6 ± 0.2, 133.9 ± 0.2 and 171.5 ± 0.2.8 . The crystalline form according to claim 1, wherein said crystalline form has a Raman spectrum containing a Raman peak shift (cm) at 1625 cm ± 2； and a solid state NMR spectrum containing a C chemical shift (ppm) at 133.9 ± 0.2.9. The crystalline form according to claim 1, wherein said crystalline form has a Raman spectrum containing a Raman peak shift (cm) at 1625 cm ± 2； and a solid state NMR spectrum containing C chemical shift (ppm) at 171.5 ± 0,1. Кристаллическая форма меглюмина 6-карбокси-2-(3,5-дихлорфенил)-бензоксазола, где указанная кристаллическая форма имеет порошковую рентгенограмму, содержащую
