MICE EXPRESSING AN IMMUNOGLOBULIN HYBRID LIGHT CHAIN WITH A HUMAN VARIABLE REGION

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专利权人:

发明人:

申请号：

HK13110524.9

公开号：

HK1183321A

申请日:

2012.11.13

申请国别(地区):

HK

年份:

2013

代理人:

摘要：

A transgenic mouse is provided comprising in its genome an endogenous » light chain immunoglobulin locus comprising a deletion of the endogenous mouse V»1-J»3-C»3-J»1-C»1 gene cluster and a deletion of a region spanning from V»2 to J»2 of the endogenous mouse V»2-V»3-J»2-C»2-J»4-C»4 gene cluster. Mouse cells and mouse embryos are also provided.

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中国工程科技知识中心

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