Provided is a hemodialysis apparatus including a hemodialyzer in which mass transfer occurs between blood and dialysate, a blood tube connecting the hemodialyzer and a patient to allow blood to flow therethrough, a blood flow controller which controls the blood flow passage through the blood tube, a dialysate supply pump supplying dialysate to the hemodialyzer, and a dialysate discharge pump discharging dialysate having passed through the hemodialyzer. The dialysate supply pump and the dialysate discharge pump further include a tube pressurizing member and a one-way valve or a roller and a roller driver. The blood tube includes a first blood tube in which blood of a patient is supplied to the hemodialyzer and a second blood tube in which blood passing through the hemodialyzer is returned to the patient.