Bold, Guido,Furet, Pascal,Gessier, Francois,Kallen, Joerg,Hergovich Lisztwan, Joanna,Masuya, Keiichi,Vaupel, Andrea
申请号：
AU2010288534
公开号：
AU2010288534A1
申请日:
2010.08.24
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The invention relates to tetra-substituted heteroarylic compounds of the formula (I) wherein X, X and X are independently C or N, Y is C-H, N-H or N, wherein the total number of nitrogen atoms represented by X, X, X and Y is 1 or 2； rings A and B are independently selected from phenyl or pyridyl； R1, R4, R', R", n and m are as defined herein. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 and/or MDM4, or variants thereof.
