БОЙД Роберт (US),ЛИ Гари (US),РЫБЧИНСКИ Филип (US)
申请号：
RU2012120759/13
公开号：
RU2012120759A
申请日:
2010.10.05
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. A compound of formula I: wherein R is a C (R) (R) (R) R is hydrogen, -OH, or halo R is hydrogen, -OH, halo or Ci ^ alkyl R is halo, Ci ^ alkyl, substituted alkyl, aryl substituted aryl, alkylcycloalkyl or substituted alkylcycloalkyl, r and may be the connected to the carbon atom to which they are attached to form a cycloalkyl ring which may optionally be substituted, is preferably halogen and more preferably by one or several fluorine atoms R is water od, Ci ^ alkyl substituted with Ci ^ alkyl, arylalkyl, substituted arylalkyl, alkylaryl, or substituted alkylaryl Z is an optional, if Z is present, represents - (CH) -, -C (= O) -, -S (= O) NH- , -S (= O) -, - C (= S) NH-, -8 (= O) -CH, C (= O) -NH-, -S (= O) -NRR, -C (= O ) alkyl or -C (= O) CH (NH) CH R is hydrogen, Ci ^ alkyl or substituted Ci ^ alkyl R is hydrogen, Ci ^ alkyl or substituted Ci ^ alkyl R is hydrogen, Ci ^ alkyl, substituted alkyl, aryl, substituted aryl, alkenyl, substituted alkenyl, arylalkyl, substituted arylalkyl, alkylaryl, substituted alkylaryl, and aminoarilalkil if substituted aminoarilalkil it is -OH or halogen iRpredstavlyaet is hydrogen, halo or Ci ^ alkyl, with the proviso that r and Roba can not both be hydrogen atoms, when R is halo, Z is not present, is -OH, R, r and R are vodoroda.2 atoms. A compound of formula II: wherein R is a C (R) (R) (R) R is hydrogen, -OH, or halo R is hydrogen, -OH, halogen or CH R is halo, CH, phenyl, fluorophenyl, methylphenyl, cyclohexylmethyl, in the case where with R
