1. A method of increasing the life time of red blood cells, if necessary, comprising contacting the blood with an effective amount of (1) a compound of formula I or a pharmaceutically acceptable salt thereof； (2) a composition comprising a compound of formula I or a salt thereof, as well as a carrier； or (3) a pharmaceutically acceptable composition comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier: formula (I): or a pharmaceutically acceptable salt thereof, wherein: W, X, Y and Z are independently cleaved from CH or N； D and D are independently cleaved from the bond or NR； A is an optionally substituted aryl or optionally substituted heteroaryl； L is a bond, -C (O) -, - (CRR) -, -OC (O) -, - (CRR) -OC (O) -, - (CRR) -C (O) -, -NRC (S) -, or -NRC (O) - (where the point of attachment to R is on the left side)； R is selected from alkyl, cycloalkyl, aryl heteroaryl and ge terocyclyl； each substituted with 0-5 occurrence of R； each R is independently selected from halo, haloalkyl, alkyl, hydroxyl and —OR, or two adjacent R together with the carbon atoms to which they are attached form an optionally substituted cyclic； each R is independently selected from alkyl , acyl, hydroxyalkyl and haloalkyl； each R is independently selected from hydrogen or alkyl； each R is independently selected from hydrogen, halo, alkyl, alkoxy and halo alkoxy； or two R combined with the carbon atoms to which they are attached form an optionally substituted cycloalkyl； each R is independently selected from halo, haloalkyl, haloalkoxy, alkyl, alkynyl, nitro, cyano, hydroxyl, —C (O) R, —OC (O) R, —C (O) OR, —SR, —NRR, and —OR, or two R, together with the carbon atoms to which they are attached, form an optionally substituted heterocyclyl； n = 0, 1, or 2； m = 1, 2 or 3； h1. Способ повышения времени жизни эритроцитов при необходимости в этом, содержащий контактирование крови с эффективным количеством (1) соединения формулы I
