A method for implanting an interventional medical device, including the following steps: delivering the distal end of the puncture needle into the right atrium via the inferior vena cava; locating the puncture site on atrial septum under X-ray fluoroscopy in a first perspective angle and a second perspective angle, and puncturing the atrial septum by the puncture needle through the puncture site; delivering the medical device to the left atrial appendage or left atrium for release under X-ray fluoroscopy in a first perspective angle. The implanting method of the disclosure does not require the use of a TEE device during implementation and provides benefits of a simple operation, short operation time, and easy implementation conditions, while also be easy to promote and popularize.