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MORPHINAN DERIVATIVE
专利权人:
发明人:
申请号:
EP12829693.6
公开号:
EP2774926A1
申请日:
2012.09.07
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
A morphinan derivative represented by the following general formula (I):(in the formula, R1 represents hydrogen, C1-6 alkyl, cycloalkylalkyl (the cycloalkyl moiety has 3 to 6 carbon atoms, and the alkylene moiety has 1 to 5 carbon atoms), aralkyl (the aryl moiety has 6 to 10 carbon atoms, and the alkylene moiety has 1 to 5 carbon atoms) and the like,R2 represents hydrogen, C1-6 alkyl, C3-6 cycloalkyl, C6-10 aryl, aralkyl (the aryl moiety has 6 to 10 carbon atoms, and the alkylene moiety has 1 to 5 carbon atoms) and the like,R3, R4 and R5 represent hydrogen, hydroxy, carbamoyl, C1-6 alkoxy, C6-10 aryloxy and the like,R6a, R6b, R7, R8, R9, and R10 represent hydrogen and the like,X represents O or CH2, andY represents C=O, SO2, an atomic bond and the like), or an acid addition salt thereof is used as an analgesic.
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