MODIFIED ANTIBODY WITH IMPROVED HALF-LIFE

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专利权人:

TEVA PHARMACEUTICALS AUSTRALIA PTY LTD

发明人:

WILSON DAVID,TAURA TETSUYA

申请号：

ZA201305123

公开号：

ZA201305123B

申请日:

2013.07.08

申请国别(地区):

ZA

年份:

2014

代理人:

摘要：

The present invention relates to antibodies, immunoglobulin constructs or immunoglobulin IgG4 fusion proteins whose in vivo half-lives are increased by the combination of (i) a modified IgG4 Fc region or FcRn binding domain thereof and (ii) a modified IgG4 hinge region sequence.

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中国工程科技知识中心

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