Modified antibody with improved half-life

• 收藏
• 分享

专利权人:

Teva Pharmaceuticals Australia Pty Ltd

发明人:

Wilson, David,Taura, Tetsuya

申请号：

AU2011349049

公开号：

AU2011349049B2

申请日:

2011.12.22

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

The present invention relates to antibodies, immunoglobulin constructs or immunoglobulin IgG4 fusion proteins whose in vivo half-lives are increased by the combination of (i) a modified IgG4 Fc region or FcRn binding domain thereof and (ii) a modified IgG4 hinge region sequence.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/