ペプチドのアシル化方法及び新規アシル化剤

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专利权人:

ノヴォ ノルディスク アー/エス

发明人:

ハンセン,ルイス ブラメール

申请号：

JP2011223263

公开号：

JP5551670B2

申请日:

2011.10.07

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

PROBLEM TO BE SOLVED: To provide a method for incorporating one or more acyl groups to a peptide or a protein.SOLUTION: The method includes reacting (a) a peptide (or a protein) having at least one free amino group with an acylation agent represented by formula (I) under a basic condition in a mixture of an aprotic polar solvent and water, and saponifying the peptide ester group acylated in the above under a basic condition.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/