PROBLEM TO BE SOLVED: To enhance the working efficiency of a combine harvester by disposing a radiator, main oil cooler, and sub oil cooler so that the cooling efficiency may be improved. SOLUTION: A structure of the engine unit of a combine harvester is configured such that: the radiator (1) is disposed on one horizontal side of a machine body; an isolation frame body (3) having a proper width is provided at an outside part of the radiator (1); the main oil cooler (4) is provided for cooling oil in a transmission case and oil of a hydraulic cylinder for raising/lowering a reaper at an outside part of the isolation frame body (3); the sub oil cooler (6) for cooling oil of a hydraulic transmission for driving a traveling unit is provided to be aligned with the isolation frame body (3); and the outside of the main oil cooler (4) is covered with an engine cover (5). COPYRIGHT: (C)2011,JPO&INPIT