PROBLEM TO BE SOLVED: To provide a manufacturing method of a liquid agent reduced in the amount of dissolved oxygen, hardly deteriorated by oxidation and excellent in stability with an elapse of time.SOLUTION: The dissolved oxygen reducing liquid agent is housed in a chemical liquid container comprising a plastic of which the oxygen permeability under the condition of a temperature of 25°C and humidity RH of 60% within 12 hr after steam or hot-water sterilization treatment is 200 cm3/m2*24h*atm or above and the oxygen permeability under the condition of a temperature of 25°C and humidity RH of 60% within 12 hr when the oxygen permeability is in a steady state, is 100 cm3/m2*24h*atm or below. After the container is hermetically sealed and subjected to steam or hot-water sterilization treatment, the chemical liquid container is preserved under an environment equipped with a deoxidation means until the oxygen permeability of the plastic reaches the steady state and the concentration of dissolved oxygen of the liquid agent is reduced to 2 ppm or below.COPYRIGHT: (C)2008,JPO&INPIT【課題】溶存酸素量が低減され、酸化による変質が生じにくく、経時安定性に優れた液剤の製造方法を提供すること。【解決手段】蒸気滅菌処理または熱水滅菌処理後12時間以内における温度25℃、湿度60%RHでの酸素透過度が200cm3/m2・24h・atm以上であり、かつ酸素透過度が定常状態であるときの温度25℃、湿度60%RHでの酸素透過度が100cm3/m2・24h・atm以下であるプラスチックからなる薬液容器に、液剤を収容、密封し、蒸気滅菌処理または熱水滅菌処理を施した後、上記プラスチックの酸素透過度が定常状態に達するまで、脱酸素手段を備える環境下で上記薬液容器を保存し、上記液剤の溶存酸素濃度を2ppm以下に低減する。【選択図】図5
