LINDSLEY CRAIG W.,LINDSLEY CRAIG W.,CONN P. JEFFREY,CONN P. JEFFREY,WOOD MICHAEL R.,WOOD MICHAEL R.,HOPKINS COREY R.,HOPKINS COREY R.,MELANCON BRUCE J.,MELANCON BRUCE J.,POSLUSNEY MICHAEL S.,POSLUSNEY
申请号：
PL12843949
公开号：
PL2770997T3
申请日:
2012.10.28
申请国别(地区):
PL
年份:
2017
代理人:
摘要：
In one aspect, the invention relates to substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one analogs compounds, derivatives thereof, and related compounds which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M 1 (mAChR M 1 ) synthesis methods for making the compounds pharmaceutical compositions comprising the compounds and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions.
