Lindsley, Craig W.,Conn, P. Jeffrey,Wood, Michael R.,Hopkins, Corey R.,Melancon, Bruce J.,Poslusney, Michael S.,Engers, Darren W.
申请号：
AU2012328476
公开号：
AU2012328476B2
申请日:
2012.10.28
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
In one aspect, the invention relates to substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one analogs compounds, derivatives thereof, and related compounds which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M 1 (mAChR M 1 )； synthesis methods for making the compounds； pharmaceutical compositions comprising the compounds； and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions.
