Carbamoyl Derivatives of acid - methyl - amino - substituted acetic as novel inhibitors of NEP

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专利权人:

NOVARTIS AG

发明人:

IWAKI, YUKI,KAWANAMI, TOSHIO,KSANDER, GARY MICHAEL,MOGI, , MUNETO

申请号：

ECSP12011978

公开号：

ECSP12011978A

申请日:

2012.06.18

申请国别(地区):

EC

年份:

2012

代理人:

摘要：

The present invention provides a compound of formula I； or a pharmaceutically acceptable salt thereof, wherein R 1 , R 2 , R 3 , R 4 , R 6 , A 1 , A 2 , X 1 , sand m are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

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