Substituted bisphenyl butanoic acid derivatives as NEP inhibitors with improved in vivo Efficacy

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专利权人:

David Weninger BARNES;Dean Franklin RIGEL

发明人:

David Weninger BARNES,Dean Franklin RIGEL

申请号：

US14178312

公开号：

US20140228415A1

申请日:

2014.02.12

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention provides a compound of formula I；or a pharmaceutically acceptable salt thereof, wherein X is defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides pharmaceutical composition of the compounds of the invention and a combination of pharmacologically active agents and a compound of the invention.

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