The present invention relates to a Lactuca sativa seed designated 41-132 RZ, which may exhibit a combination of traits including resistance against downy mildew (Bremia lactucae Regel) races B1:1 to B1:28, CA-I, CA-IIA, CA-IIB, CA-III, CA-IV, CA-V, CA-VI, CA-VII, CA-VIII, and strains E138, and BGAU1, currant lettuce aphid (Nasonovia ribisnigri) biotype Nr:0, corky root rot (Sphingomonas suberifaciens), as well as broad base leaves, and slow bolting. The present invention also relates to a Lactuca sativa plant produced by growing the 41-132 RZ seed. The invention further relates to methods for producing the lettuce cultivar, represented by lettuce variety 41-132 RZ.