PD-L1-EXPRESSING HEMOPOETIC STEM CELLS AND APPLICATIONS

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专利权人:

ЗЕ ЧИЛДРЕН'С МЕДИКАЛ СЕНТЕР КОРПОРЕЙШН (US)

发明人:

ФЛОРИНА Паоло (US)

申请号：

RU2018106515

公开号：

RU2018106515A

申请日:

2016.07.20

申请国别(地区):

RU

年份:

2019

代理人:

摘要：

Embodiments disclosed here provide engineered modified hematopoietic stem cells (HSCs), artificially prostaglandin E2 (PGE2)-stimulated HSCs, compositions comprising these HSCs, methods of using these modified HSCs for treating autoimmune diseases and disorders and for suppressing the immune system. In particular, the engineered modified HSCs or PGE2-stimulated HSCs express the surface marker, programmed cell death-1 ligand 1 (PD-L1).

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中国工程科技知识中心

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http://www.ckcest.cn/home/