6-BRIDGED HETEROARYLDIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

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专利权人:

F. HOFFMANN - LA ROCHE AG

发明人:

GUO, LEI,HU, TAISHAN,HU, YIMIN,KOCER, BUELENT,KOU, BUYU,LI, GANGQIN,LIN, XIANFENG,LIU, HAIXIA,SHEN, HONG,SHI, HOUGUANG,WU, GUOLONG,ZHANG, ZHISEN,ZHOU, MINGWEI,ZHU, WEI

申请号：

PH12015502443

公开号：

PH12015502443A1

申请日:

2015.10.22

申请国别(地区):

PH

年份:

2016

代理人:

摘要：

The invention provides novel compounds having the general formula: wherein R1, R2, R3 and R4 are as defined in the description and in the claims, as well as or pharmaceutically acceptable salts, or tautomerism isomers, or enantiomers, or diastereomers thereof. The invention also contains compositions including the compounds and methods of using the compounds for the treatment or prophylaxis of hepatitis B virus infection.

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中国工程科技知识中心

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http://www.ckcest.cn/home/