6-bridged heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis B virus infection

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专利权人:

Hoffmann-La Roche Inc.

发明人:

Lei Guo,Taishan Hu,Yimin Hu,Buelent Kocer,Buyu Kou,Gangqin Li,Xianfeng Lin,Haixia Liu,Hong Shen,Houguang Shi,Guolong Wu,Zhisen Zhang,Mingwei Zhou,Wei Zhu

申请号：

US14991786

公开号：

US09758530B2

申请日:

2016.01.08

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The invention provides novel compounds having the general formula:wherein R1, R2, R3 and R4 are as defined in the description and in the claims, as well as or pharmaceutically acceptable salts, or tautomerism isomers, or enantiomers, or diastereomers thereof. The invention also contains compositions including the compounds and methods of using the compounds.

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