6-BRIDGED HETEROARYLDIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

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专利权人:

F. Hoffmann-La Roche AG

发明人:

GUO, Lei,HU, Taishan,HU, Yimin,KOCER, Buelent,KOU, Buyu,LI, Gangqin,LIN, Xianfeng,LIU, Haixia,SHEN, Hong,SHI, Houguang,WU, Guolong,ZHANG, Zhisen,ZHOU, Mingwei,ZHU, Wei

申请号：

EP14724735

公开号：

EP2997032B1

申请日:

2014.05.16

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The invention provides novel compounds having the general formula: wherein R1, R2, R3 and R4 are as defined in the description and in the claims, as well as or pharmaceutically acceptable salts, or tautomerism isomers, or enantiomers, or diastereomers thereof. The invention also contains compositions including the compounds and methods of using the compounds.

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