Guy Hermans,Peter Verheesen,Edward Dolk,Hendricus Renerus Jacobus Mattheus Hoogenboom,Michael John Scott Saunders,Johannes Joseph Wilhelmus De Haard,Renee de Bruin
申请号：
US12448260
公开号：
US08907065B2
申请日:
2007.12.17
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to amino acid sequences that block the interaction between (a target on) an antigen presenting cell (APC) and (a target on) a T-cell. More particularly, the present invention relates to amino acid sequences that are directed against (as defined herein) a target on an APC (also referred to herein as “APC target”) or a target on a T-cell (also referred to herein as “T-cell target”). The invention further relates to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.
