CLOSED-SYSTEM MANUFACTURING PROCESS FOR CAR-T CELLS

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专利权人:

SEATTLE CHILDREN'S HOSPITAL (DBA SEATTLE CHILDREN'S RESEARCH INSTITUTE)

发明人:

JENSEN, Michael C.,GUSTAFSON, Joshua

申请号：

SG11202007441T

公开号：

SG11202007441TA

申请日:

2019.02.04

申请国别(地区):

SG

年份:

2020

代理人:

摘要：

Some embodiments provided herein relate to methods and compositions for making genetically modified T cells. In some such embodiments, CD4+ and CD8+ T cells are cultured in a single serum-free volume. In some embodiments, co-cultured CD4+ and CD8+ T cells can be transduced with a lentiviral vector, and a population of transduced T cells can be harvested within a shorter period of time than other conventional methods.

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中国工程科技知识中心

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http://www.ckcest.cn/home/