Brian Budzik;Ian Thomson Forbes;Jian Jin;David Gwyn Cooper;Dongchuan Shi;Vincenzo Garzya;Graham Walker
发明人:
Brian Budzik,David Gwyn Cooper,Ian Thomson Forbes,Vincenzo Garzya,Jian Jin,Dongchuan Shi,Graham Walker
申请号：
US11852455
公开号：
US08481566B2
申请日:
2007.09.10
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Compounds of formula (I) and salts and solvates are provided:wherein R4 is fluoro, R5 is selected from hydrogen, halogen, cyano, C1-6alkyl, C1-6alkyl substituted with one or more fluorine atoms, C1-6alkoxy, and C1-6alkoxy substituted with one or more fluorine atoms； and R6 is selected from halogen, cyano, C1-6alkyl, C1-6alkyl substituted with one or more fluorine atoms, C3-6cycloalkyl, C3-6cycloalkyl substituted with one or more fluorine atoms, C1-6alkoxy and C1-6alkoxy substituted with one or more fluorine atoms, and Q is hydrogen or C1-6alkyl. The compounds are expected to be useful for therapy, for example in the treatment of psychotic disorders and cognitive impairment.
