Brian Budzik;David Gwyn Cooper;Ian Thomson Forbes;Vincenzo Garzya;Jian Jin;Dongchuan Shi;Paul William Smith;Graham Walker
发明人:
Brian Budzik,David Gwyn Cooper,Ian Thomson Forbes,Vincenzo Garzya,Jian Jin,Dongchuan Shi,Paul William Smith,Graham Walker
申请号:
US12088465
公开号:
US08283364B2
申请日:
2006.09.27
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Compounds of formula (I) and salts are provided:wherein R4 is fluoro, R5 is selected from hydrogen, halogen, cyano, C1-6alkyl, C1-6alkyl substituted with one or more fluorine atoms, C1-6alkoxy, and C1-6alkoxy substituted with one or more fluorine atoms; and R6 is selected from halogen, cyano, C1-6alkyl, C1-6alkyl substituted with one or more fluorine atoms, C3-6cycloalkyl, C3-6cycloalkyl substituted with one or more fluorine atoms, C1-6alkoxy and C1-6alkoxy substituted with one or more fluorine atoms, and Q is hydrogen or C1-6alkyl. The compounds are expected to be useful for therapy, for example in the treatment of psychotic disorders and cognitive impairment.