William M. Jone;John M. Keith;J. Guy Breitenbucher
发明人:
J. Guy Breitenbucher,John M. Keith,William M. Jone
申请号:
US13375868
公开号:
US20120083476A1
申请日:
2010.06.04
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Certain heteroaryl-substituted spirocyclic diamine urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, energy metabolism disorders, and movement disorders (e.g., multiple sclerosis).