John M. Keith;Natallie A. Hawryluk;Mark S. Tichenor;Jeffrey E. Merit;J. Guy Breitenbucher;Alison L. Chambers
发明人:
J. Guy Breitenbucher,Mark S. Tichenor,Jeffrey E. Merit,John M. Keith,Natallie A. Hawryluk,Alison L. Chambers
申请号:
US13375855
公开号:
US20120088741A1
申请日:
2010.06.04
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Certain aryl-substituted heterocyclic urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, energy metabolism disorders, and movement disorders (e.g., multiple sclerosis).