(4-Chloro-pyridin-3-yl) - (2, 2-difluoro-benzo [1,3] dioxol- Amide is described. (4-Chloro-pyridin-3-yl) -amide was prepared by reacting 4- (2,2-difluoro-benzo [1,3] dioxol-5-ylmethyl) -piperazine- A pharmaceutical composition for the treatment of disease states, disorders and conditions mediated by hydrolase (FAAH) activity such as anxiety, pain, inflammation, sleep disorders, eating disorders, energy metabolism disorders and movement disorders (e.g., multiple sclerosis) And methods of treatment. The title compound was also prepared from 4- (2,2-difluoro-benzo [1,3] dioxol-5-ylmethyl) -piperazine-1- carboxylic acid (4-chloro-pyridin- A method of synthesizing is disclosed.FAAH 조절제로서 유용한 4-(2,2-다이플루오로-벤조[1,3]다이옥솔-5-일메틸)-피페라진-1-카르복실산 (4-클로로-피리딘-3-일)-아미드가 기재된다. 4-(2,2-다이플루오로-벤조[1,3]다이옥솔-5-일메틸)-피페라진-1-카르복실산 (4-클로로-피리딘-3-일)-아미드는 지방산 아미드 하이드롤라제 (FAAH) 활성에 의해 매개되는 질환 상태, 장애 및 병상, 예컨대 불안, 통증, 염증, 수면 장애, 섭식 장애, 에너지 대사 장애 및 운동 장애 (예컨대, 다발성 경화증)의 치료를 위한 약제학적 조성물 및 치료 방법에서 사용될 수 있다. 또한, 4-(2,2-다이플루오로-벤조[1,3]다이옥솔-5-일메틸)-피페라진-1-카르복실산 (4-클로로-피리딘-3-일)-아미드를 합성하는 방법이 개시된다.
