PROCÉDÉ DE PRODUCTION DE NANOPARTICULES HYBRIDES AMORPHES STABLES COMPRENANT AU MOINS UN INHIBITEUR DE LA PROTÉINE KINASE ET AU MOINS UN CONSTITUANT POLYMÈRE STABILISANT ET MATRICIEL
BRISANDER, MAGNUS,DEMIRBÜKER, MUSTAFA,JESSON, GÉRALD,MALMSTEN, MARTIN,DÉRAND, HELENE
申请号:
EP13736318
公开号:
EP2802314A4
申请日:
2013.01.11
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.