Karl Schoenafinger,Henning Steinhagen,Bodo Scheiper,Uwe Heinelt,Volkmar Herrmann,Matthias Herrmann
申请号:
US13652898
公开号:
US08871798B2
申请日:
2012.10.16
申请国别(地区):
US
年份:
2014
代理人:
摘要:
This disclosure relates to compounds of formula I:wherein R1, R2, R3, R4, X and Y have the meanings denoted in the disclosure. The compounds of formula I have antithrombotic activity and in particular inhibit the protease-activated receptor 1 (PAR1). The disclosure further relates to a method for producing the compound of formula I and to the use thereof as a pharmaceutical product.