Imidazopyridazines as PAR1 inhibitors, production thereof, and use as medicaments

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专利权人:

Uwe Heinelt;Volkmar Wehner;Karl Schoenafinger;Matthias Herrmann;Henning Steinhagen

发明人:

Uwe Heinelt,Volkmar Wehner,Matthias Herrmann,Karl Schoenafinger,Henning Steinhagen

申请号：

US12851198

公开号：

US08598177B2

申请日:

2010.08.05

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The invention relates to novel compounds of formula Iwhere R1, R2, R3, R4, R5, R6, R7, R8, R9, Q1, Q2 and Q3 are each as defined below. The compounds of formula I have antithrombotic activity and inhibit especially protease-activated receptor 1 (PAR1). The invention further relates to a process for preparing the compound of formula I and to the use thereof as a medicament.

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