Triazolium salts as PAR1 inhibitors, production thereof, and use as medicaments

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专利权人:

Uwe Heinelt;Volkmar Wehner;Karl Schoenafinger;Matthias Herrmann;Henning Steinhagen

发明人:

Uwe Heinelt,Volkmar Wehner,Matthias Herrmann,Karl Schoenafinger,Henning Steinhagen

申请号：

US12851219

公开号：

US08198272B2

申请日:

2010.08.05

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The invention relates to novel compounds of formula Iwhere X, A−, Q1, Q2, Q3, R2, R3, R4, R5, R6, R7, R8 and R9 are each as defined below. The compounds of formula I have antithrombotic activity and inhibit especially protease-activated receptor 1 (PAR1). The invention further relates to a process for preparing the compound of formula I and to the use thereof as a medicament.

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