PYRIDYL-VINYLE-PYRROLES TRICYCLIQUES COMME INHIBITEURS DE PAR1

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专利权人:

SANOFI

发明人:

SCHOENAFINGER, KARL,STEINHAGEN, HENNING,SCHEIPER, BODO,HEINELT, UWE,WEHNER, VOLKMAR,HERRMANN, MATTHIAS

申请号：

EP11715496.3

公开号：

EP2558465B1

申请日:

2011.04.14

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

This disclosure relates to compounds of formula I: wherein R1, R2, R3, R4, X and Y have the meanings denoted in the disclosure. The compounds of formula I have antithrombotic activity and in particular inhibit the protease-activated receptor 1 (PAR1). The disclosure further relates to a method for producing the compound of formula I and to the use thereof as a pharmaceutical product.

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