HILPERT, Kurt,HUBLER, Francis,KIMMERLIN, Thierry,RENNEBERG, Dorte,STAMM, Simon
申请号：
ES13824192
公开号：
ES2618056T3
申请日:
2013.12.11
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A compound of formula (I), ** Formula ** in which R 1 represents a heteroaryl or aryl group, groups that are independently unsubstituted, mono-, di- or trisubstituted, in which the substituents are independently selected from the group that it consists of (C1-C4) alkyl, (C3-C6) cycloalkyl, (C1-C4) alkoxy, (C1-C3) fluoroalkyl (C1-C3) fluoroalkoxy, hydroxy, halogen and phenoxy； R2 represents - heterocyclyl, which is unsubstituted, mono- or di-substituted, in which the substituents are independently selected from (C1-C4) alkyl, (C1-C4) alkylcarbonyl, (C1-C4) alkoxycarbonyl, (C1-alkylsulfonyl) -C4) and halogen； - heterocyclyloxy； - cycloalkyl (C3-C6), which is unsubstituted or mono- or di-substituted with halogen； - cycloalkyloxy (C3-C6)； - N-cycloalkyl (C3-C6) -amino； - N-cycloalkyl (C3-C6) methyl amino； - (C3-C6) alkyl； - (C2-C6) alkoxy； - N-alkylamino (C1-C4)； - N, N-di- [(C1-C4) alkyl] -amino； or - N-arylmethyl-N-(C1-C4) alkyl amino； R3 represents hydrogen or halogen； R4 represents hydrogen, fluorine, chlorine, (C1-C4) alkyl, (C1-C4) alkoxy, (C1-C4) alkylcarbonyl, hydroxy (C1-C4) alkyl, hydroxy (C2-C4) alkoxy, alkoxy (C1-C2) -alkyl (C1-C4) or (C1-C4) alkoxy-(C2-C4) alkoxy； R5 represents hydrogen or (C1-C4) alkyl； and R5 represents fluorine, chlorine, methyl, ethyl or fluoroalkyl (C1-C2)； or a salt of said compound,Un compuesto de fórmula (I),**Fórmula** en la que R1 representa un grupo heteroarilo o arilo, grupos que están independientemente no sustituidos, mono-, di- o trisustituidos, en el que los sustituyentes están independientemente seleccionados del grupo que consiste en alquilo (C1- C4), cicloalquilo (C3-C6), alcoxi (C1-C4), fluoroalquilo (C1-C3), fluoroalcoxi (C1-C3), hidroxi, halógeno y fenoxi； R2 representa - heterociclilo, que está sin sustituir, mono- o di-sustituido, en los que los sustituyentes se seleccionan independientemente de alquilo (C1-C4), alquilcarbonilo (C1-C4), alcoxicarbonilo (C1-C4), alquilsulfonilo (C1-C4) y halógeno； - heterocicliloxi； -
