The present invention relates to probiotic bacterial strains belonging to the genus Bifidobacterium and/or probiotic cell extracts (PCEs) thereof, having immunostimulating, anti-inflammatory and antioxidant properties. Furthermore, the present invention relates to a composition comprising a mixture comprising or, alternatively, consisting of said probiotic bacterial strains belonging to the genus Bifidobacterium and/or probiotic cell extracts (PCEs) thereof, having immunostimulating, anti-inflammatory and antioxidant properties. Finally, the present invention relates to said composition for use in the preventive and/or curative treatment of (i) inflammatory diseases, (ii) viral, bacterial, fungal or protozoan diseases, (iii) infections, and (iv) flu, cold or fever.