Christine Lowe,Nandini Rudra-Ganguly,Faisal Hayat Malik,Sung Ju Moon,Josh Snyder,Hector Avina,Cyrus Virata,Linnette Capo,Gao Liu
申请号：
US15065707
公开号：
US20160272716A1
申请日:
2016.03.09
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Antibody drug conjugates (ADCs) that bind to FLT3 protein and variants thereof are described herein. FLT3 exhibits a distinct and limited expression pattern in normal adult tissue(s), and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADCs of the invention provide a therapeutic composition for the treatment of cancer.
