Nandini RUDRA-GANGULY,Christine LOWE,Faisal Hayat MALIK,Sung Ju MOON,Josh SNYDER,Hector AVINA,Cyrus VIRATA,Linnette CAPO,Gao LIU
申请号：
US15556587
公开号：
US20180037657A1
申请日:
2016.03.09
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Antibody drug conjugates (ADCs) that bind to FLT3 protein and variants thereof are described herein. FLT3 exhibits a distinct and limited expression pattern in normal adult tissue(s), and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADCs of the invention provide a therapeutic composition for the treatment of cancer.
