ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO FLT3 PROTEINS

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专利权人:

AGENSYS; INC.

发明人:

RUDRA-GANGULY, NANDINI,LOWE, CHRISTINE,MALIK, FAISAL HAYAT,MOON, SUNG JU,SNYDER, JOSH,AVINA, HECTOR,VIRATA, CYRUS,CAPO, LINNETTE,LIU, GAO

申请号：

CA2978631

公开号：

CA2978631A1

申请日:

2016.03.09

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

Antibody drug conjugates (ADCs) that bind to FLT3 protein and variantsthereof are described herein. FLT3 exhibitsa distinct and limited expression pattern in normal adult tissue(s), and isaberrantly expressed in the cancers listed in Table I. Consequently,the ADCs of the invention provide a therapeutic composition for the treatmentof cancer.

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中国工程科技知识中心

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http://www.ckcest.cn/home/