GUDAS JEAN,AN ZILI,MORRISON KAREN JANE MEYRICK,BENJAMIN DENNIS,SENTER PETER D,JAKOBOVITS AYA,MORRISON ROBERT KENDALL,JIA XIAO-CHI,MOSER RUTH
申请号:
ZA201107293
公开号:
ZA201107293B
申请日:
2011.10.05
申请国别(地区):
ZA
年份:
2012
代理人:
摘要:
Antibody drug conjugates (ADCs) that bind to 24P4C12 protein and variants thereof are described herein. 24P4C12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADCs of the invention provide a therapeutic composition for the treatment of cancer.